“Who thinks of the bone as being an endocrine organ? You think of the adrenal gland, you think of the pituitary, you don’t think of bone.”
In 2011, he showed that bones play a crucial role in male reproduction: mice that did not produce osteocalcin had abnormally low levels of testosterone and were sterile. Mice that produced high levels, on the other hand, had more testosterone and bred more frequently.
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Photograph: Marcel van den Bergh/Hollandse Hoogte/Redux
Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions